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Tosis (Fig. 2), and C5a in conjunction with antibody increased VWF release only slightly above levels induced by antibody alone (Fig. 3). Although complement fixation by antibody is a component of acute rejection, our results suggest that antibody can activate exocytosis independent of complement (11).Antibody Induces Exocytosis in Vivo. The F(ab )2 fragment of thethelial cells through their C5a r
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